How long is a piece of string. You could literally write a book on how to play AK preflop!
but for generalisation,assuming 100bb stacks, I would say I am more inclined to 4bet and get it in OOP. Versus looser players who are likely 3bet folding I may elect to flat 3bets IP some % of the time to keep dominated hands in (AQ/KQ/AJ) which will stack off if they hit TP but will fold pre if we 4bet. If we 3bet an EP opener I am *nearly* always calling a shove - dependent on the villain obv.
